Skeletal Myxoid Chondrosarcoma of the Fibula
نویسندگان
چکیده
Chondrosarcoma of the bone is second most common malignant bone tumor next only to osteosarcoma. The most common type of chondrosarcoma is the conventional chondrosarcoma (90%). The myxoid variant is a rare occurrence and is associated with a worse outcome as opposed to conventional type. There are only a few references of this tumor in literature. The most common location for skeletal myxoid chondrosarcoma is the femur. There is similarity in light microscopic features in extraskeletal chondrosarcoma and skeletal myxoid chondrosarcoma there exist elementary differences at ultrastructural and molecular levels. Skeletal myxoid chondrosarcoma presents as a well-defined osteolytic lesion with endosteal scalloping, cortical invasion and expansion on radiography. Myxoid chondrosarcoma of the bone has a more aggressive clinical course than conventional intramedullary chondrosarcoma, with patients commonly developing distant metastases and local recurrence. The purpose of our article is to report this rare myxoid chondrosarcoma of the proximal fibula, which has not been reported at this anatomical site previously with an emphasis on its radiological features and histopathological features.
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